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Multifocal primary bone lymphoma: durable complete remission after R-CHOP chemotherapy.

Abstract
Primary bone lymphoma (PBL) is a type of non-Hodgkin's lymphoma predominantly affecting the skeletal system. PBL is an extremely rare cancer in adults affecting mainly the axial skeleton. The extent of bone involvement in these patients is variable. Most of the cases reported had single or a few skeletal lesions. We report a patient who had extensive multifocal lymphoma involving the axial skeleton and a very good and durable response to R-CHOP chemotherapy.
AuthorsMuhajir Mohamed, Terry Brain, Sharad Sharma
JournalBMJ case reports (BMJ Case Rep) Vol. 2013 (May 22 2013) ISSN: 1757-790X [Electronic] England
PMID23704456 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Monoclonal, Murine-Derived
  • R-CHOP protocol
  • Rituximab
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone
Topics
  • Antibodies, Monoclonal, Murine-Derived (therapeutic use)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Bone Neoplasms (drug therapy)
  • Bone and Bones (pathology)
  • Cyclophosphamide (therapeutic use)
  • Doxorubicin (therapeutic use)
  • Humans
  • Lymphoma, Non-Hodgkin (drug therapy)
  • Male
  • Middle Aged
  • Prednisone (therapeutic use)
  • Remission Induction
  • Rituximab
  • Vincristine (therapeutic use)

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