Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass.

Abstract

A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwent right total and left subtotal thyroidectomy, following the diagnosis of nodular goiter; however, postoperative histopathological evaluation demonstrated primary Burkitt's lymphoma of the thyroid gland. The tumor was staged as stage 1, and R-hyper-CVAD protocol (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) was administered. The protocol was changed to R-CHOP after 4 cycles due to recurrent grade III/IV cytopenias and febrile neutropenia. The PET-CT scans performed after chemotherapy and at the 6-month follow-up were normal. In summary, we reported a case with a diagnosis of Burkitt's lymphoma, which is a rare type of primary thyroid lymphoma.

• Authors: Ibrahim Yildiz, Fatma Sen, Bahtiyar Toz, Leyla Kilic, Mehmet Agan, Mert Basaran
• Journal: Case reports in oncology (Case Rep Oncol) Vol. 5 Issue 2 Pg. 388-93 (May 2012) ISSN: 1662-6575 [Electronic] Switzerland
• PMID: 23524885 (Publication Type: Case Reports)