Abstract | BACKGROUND: MATERIALS AND METHODS: A retrospective review of 32 patients with clear cell renal cell carcinoma was evaluated. All patients underwent magnetic resonance imaging (MRI) and 22 out of 32 patients also underwent a computed tomography (CT) scan. Hemorrhage was classified into 3 different categories according to shape and distribution. Histopathology was obtained from all masses by radical nephrectomy. The ability to detect the presence of hemorrhage using CT, non-contrast conventional MRI and SWI was evaluated, and the patterns of hemorrhage were compared. RESULTS: Using pathologic results as the gold standard, the sensitivities of non-contrast conventional MRI, SWI and CT in detecting hemorrhage in clear cell renal cell carcinoma were 65.6%, 100% and 22.7%, respectively. Accuracy of non-contrast conventional MRI and SWI in evaluating hemorrhagic patterns were 31.3% and 100%, respectively. CONCLUSION: These results demonstrate that SWI can better reveal hemorrhage and characterize the pattern more accurately than either non-contrast conventional MRI or CT. This suggests that SWI is the technique of choice for detecting hemorrhagic lesions in patients with renal cancer.
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Authors | Wei Xing, Xiaozhou He, Mohammad A Kassir, Jie Chen, Jiule Ding, Jun Sun, Jiani Hu, Zishu Zhang, E Mark Haacke, Yongming Dai |
Journal | PloS one
(PLoS One)
Vol. 8
Issue 2
Pg. e57691
( 2013)
ISSN: 1932-6203 [Electronic] United States |
PMID | 23451259
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- Carcinoma, Renal Cell
(diagnosis, physiopathology)
- Female
- Hemorrhage
(diagnosis)
- Humans
- Kidney Neoplasms
(diagnosis, physiopathology)
- Magnetic Resonance Imaging
(methods)
- Male
- Middle Aged
- Retrospective Studies
- Tomography, X-Ray Computed
(methods)
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