Abstract | OBJECTIVE: Although diabetes increases the risk of cardiovascular disease (CVD) and mortality, the dose-response relationship between fasting glucose levels below those diagnostic of diabetes with cardiovascular events has not been well characterized. RESEARCH DESIGN AND METHODS: A prospective cohort study of more than one million Koreans was conducted with a mean follow-up of 16 years. A total of 1,197,384 Korean adults with no specific medical conditions diagnosed were classified by baseline fasting serum glucose level. Associations of fasting glucose level with CVD incidence and mortality, stroke incidence and mortality, and all-cause mortality were analyzed using multivariate proportional hazards regression. RESULTS: CONCLUSIONS:
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Authors | Chanshin Park, Eliseo Guallar, John A Linton, Duk-Chul Lee, Yangsoo Jang, Dong Koog Son, Eun-Jeong Han, Soo Jin Baek, Young Duk Yun, Sun Ha Jee, Jonathan M Samet |
Journal | Diabetes care
(Diabetes Care)
Vol. 36
Issue 7
Pg. 1988-93
(Jul 2013)
ISSN: 1935-5548 [Electronic] United States |
PMID | 23404299
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Blood Glucose
(metabolism)
- Cardiovascular Diseases
(blood, epidemiology)
- Coronary Disease
(blood, epidemiology)
- Fasting
(blood)
- Female
- Humans
- Male
- Middle Aged
- Prospective Studies
- Risk Factors
- Stroke
(blood, epidemiology)
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