Mechanical thrombectomy for cerebral venous sinus thrombosis: a comprehensive literature review.

Abstract

BACKGROUND:

Endovascular treatment of cerebral venous sinus thrombosis (CVST) includes pharmacological and mechanical thrombolysis.

METHODS:

The authors searched the English literature on CVST from 1990 to 2012 for all case reports or case series of mechanical thrombectomy.

RESULTS:

A total of 64 patients were treated in all published studies. The techniques for mechanical thrombectomy included rheolytic thrombectomy with an AngioJet device (46.9%), clot retraction with the Penumbra system (4.7%), clot retraction with a Fogarty catheter (1.6%), clot retraction with a microsnare (3.1%), balloon venoplasty without stenting (18.7%), balloon venoplasty with stenting (4.7%), and an amalgam of techniques (18.7%). Nine (16.1%) patients died. At the most recent follow-up, 40 (62.5%) patients had no disability or minor disability and 7 (10.9%) patients had major disability.

CONCLUSION:

Randomized multiinstitutional clinical trials with larger number of participants are needed to sufficiently compare the effect of intrasinus thrombolysis and mechanical thrombectomy to standard-of-care anticoagulation therapy.

• Authors: Afshin Borhani Haghighi, Mojtaba Mahmoodi, Randall C Edgell, Salvador Cruz-Flores, Hosein Ghanaati, Mohammad Jamshidi, Osama O Zaidat
• Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (Clin Appl Thromb Hemost) Vol. 20 Issue 5 Pg. 507-15 (Jul 2014) ISSN: 1938-2723 [Electronic] United States
• PMID: 23297370 (Publication Type: Journal Article, Review)
• Copyright: © The Author(s) 2013.

Topics

• Humans
• Mechanical Thrombolysis (adverse effects, methods)
• Sinus Thrombosis, Intracranial (pathology, therapy)