[Clinical re-evaluation of effects of two different "cocktail therapy" to prevent from phlebitis induced by Chansu injection].

Abstract

OBJECTIVE:

To re-evaluate the effects of different "cocktail therapy" to prevent from phlebitis induced by Chansu injection.

METHOD:

Patients treated with Chansu injection were divided randomLy into 4 groups with 90 per group, control group, phentolaminum group, the magnesium sulfate group-phentolaminum group, and anisodamine-phentolaminum group. Patients in the control group only received the routine nursing treatment, and patients in the various experiment group received different interventions. The comparison was made in the morbidity and the starting time of occurrence of phlebitis, the severity of pain, duration of pain.

RESULT:

The morbidity of phlebitis was 8%, 8%, 6%, respectively. The starting time of phlebitis occurrence was (22 +/- 4), (27 +/- 5), (28 +/- 7) h, respectively. The NRS of pain was (4.75 +/- 1.51), (3.27 +/- 1.02), (2.71 +/- 1.63), respectively. The duration time of pain was (4.25 +/- 1.36), (2.51 +/- 1.05), (2.19 +/- 1.13) d respectively. In control group, the morbidity of phlebitis, the starting time of occurrence of phlebitis, the severity of pain, duration of pain was 30%, (16 +/- 4) h, (6.34 +/- 1.21), (5.47 +/- 1.07) d, respectively. As compared with the control group, a significance difference was found between every group in three test groups and control group respectively (P<0.05).

CONCLUSION:

The morbidity and the starting time of occurrence of phlebitis, the severity of pain, duration of pain was significantly reduced respectively by two different "cocktail therapy".

• Authors: Yu-Bin Zhao, Zhe Hao, Hong-Dan Zhang, Yan-Ming Xie
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 37 Issue 18 Pg. 2739-41 (Sep 2012) ISSN: 1001-5302 [Print] China
• PMID: 23285923 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Bufanolides
• Solanaceous Alkaloids
• chan su
• anisodamine
• Magnesium Sulfate
• Phentolamine

Topics

• Adult
• Aged
• Animals
• Anura
• Bufanolides (administration & dosage, adverse effects)
• Drug Therapy, Combination
• Humans
• Magnesium Sulfate (therapeutic use)
• Male
• Middle Aged
• Phentolamine (therapeutic use)
• Phlebitis (drug therapy, etiology, prevention & control)
• Solanaceous Alkaloids (therapeutic use)
• Young Adult