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Brentuximab vedotin combined with donor lymphocyte infusions for early relapse of Hodgkin lymphoma after allogeneic stem-cell transplantation induces tumor-specific immunity and sustained clinical remission.

AuthorsSebastian Theurich, Joke Malcher, Kerstin Wennhold, Alexander Shimabukuro-Vornhagen, Jens Chemnitz, Udo Holtick, Anke Krause, Carsten Kobe, Deniz Kahraman, Andreas Engert, Christof Scheid, Geothy Chakupurakal, Michael Hallek, Michael von Bergwelt-Baildon
JournalJournal of clinical oncology : official journal of the American Society of Clinical Oncology (J Clin Oncol) Vol. 31 Issue 5 Pg. e59-63 (Feb 10 2013) ISSN: 1527-7755 [Electronic] United States
PMID23269992 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents
  • HLA-A2 Antigen
  • Immunoconjugates
  • KLRB1 protein, human
  • Ki-1 Antigen
  • NK Cell Lectin-Like Receptor Subfamily B
  • Brentuximab Vedotin
Topics
  • Antineoplastic Agents (administration & dosage, adverse effects, therapeutic use)
  • Apoptosis (immunology)
  • Brentuximab Vedotin
  • CD4-Positive T-Lymphocytes (immunology)
  • Combined Modality Therapy
  • Drug Administration Schedule
  • Graft vs Host Disease (etiology)
  • HLA-A2 Antigen (immunology)
  • Hematopoietic Stem Cell Transplantation (adverse effects)
  • Hodgkin Disease (drug therapy, immunology, surgery, therapy)
  • Humans
  • Immunoconjugates (administration & dosage, adverse effects, therapeutic use)
  • Immunotherapy, Adoptive (methods)
  • Ki-1 Antigen (antagonists & inhibitors)
  • Lymphocytes (immunology)
  • NK Cell Lectin-Like Receptor Subfamily B (immunology)
  • Polyneuropathies (chemically induced)
  • Recurrence
  • Remission Induction
  • Shock, Septic (etiology)
  • T-Lymphocytes (immunology)
  • T-Lymphocytes, Cytotoxic (immunology)
  • Th17 Cells (immunology)
  • Thrombocytopenia (chemically induced)
  • Transplantation, Homologous
  • Treatment Outcome

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