Abstract | BACKGROUND: METHODS: This study involved patients with previously untreated PTC that had metastasized to the lateral neck, and who underwent total thyroidectomy with central and lateral neck dissection. Histopathological findings were compared with ultrasound results for various neck levels. Clinical and histopathological factors that predicted level V metastasis were identified. RESULTS: Of 143 patients, 26 (18·2 per cent) had lymph node metastasis at level V. The sensitivity and positive predictive value of ultrasonography for level V metastasis were 46·2 and 30·0 per cent respectively. Univariable analysis showed that male sex, extranodal disease extension, a metastatic lymph node ratio in the ipsilateral lateral neck of more than 0·2, and simultaneous involvement of ipsilateral levels II-IV or level III were associated with ipsilateral level V metastasis. Multivariable analysis revealed an independent association between macroscopic extranodal disease extension and level V metastasis (odds ratio 26·05, 95 per cent confidence interval 5·63 to 120·56; P < 0·001). CONCLUSION:
|
Authors | M J Shim, J-L Roh, G Gong, K-J Choi, J H Lee, S-H Cho, S Y Nam, S Y Kim |
Journal | The British journal of surgery
(Br J Surg)
Vol. 100
Issue 4
Pg. 497-503
(Mar 2013)
ISSN: 1365-2168 [Electronic] England |
PMID | 23254479
(Publication Type: Journal Article)
|
Copyright | Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. |
Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Biopsy, Fine-Needle
(methods)
- Carcinoma, Papillary
(diagnostic imaging, secondary, surgery)
- Female
- Humans
- Image-Guided Biopsy
(methods)
- Lymphatic Metastasis
- Male
- Middle Aged
- Neck Dissection
(methods)
- Preoperative Care
(methods)
- Retrospective Studies
- Thyroid Neoplasms
(diagnostic imaging, secondary, surgery)
- Ultrasonography
- Young Adult
|