Ulcerative colitis associated with isolated unilateral hypoglossal nerve palsy.

Abstract

We herein describe a rare case of ulcerative colitis associated with unilateral hypoglossal nerve palsy. A 64-year-old woman developed severe active ulcerative colitis and was treated with prednisolone. The dose of oral prednisolone was reduced to 7.5 mg/day, following which the patient noticed slight dysphagia and a speech disturbance. She was diagnosed with unilateral hypoglossal nerve palsy, which was thought to be caused by mononeuritis. She was treated with intravenous methylprednisolone at a dose of 500 mg/day, which improved the neuropathy. When the neuropathy occurred, the patient was in a mildly active stage of ulcerative colitis. We concluded that the mononeuritis observed in the present case was likely an extraintestinal manifestation of ulcerative colitis.

• Authors: Kousaku Kawashima, Shunji Ishihara, Koji Doi, Yusuke Uemura, Yasuhiko Ohno, Kosuke Fukuda, Koji Onishi, Yasumasa Tada, Akihiko Oka, Ryusaku Kusunoki, Nobuhiko Fukuba, Takafumi Yuki, Yoshikazu Kinoshita
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 51 Issue 22 Pg. 3135-7 ( 2012) ISSN: 1349-7235 [Electronic] Japan
• PMID: 23154719 (Publication Type: Case Reports, Journal Article)

Chemical References

• Prednisolone
• Methylprednisolone

Topics

• Colitis, Ulcerative (complications, drug therapy, pathology)
• Female
• Humans
• Hypoglossal Nerve Diseases (complications, drug therapy)
• Methylprednisolone (therapeutic use)
• Middle Aged
• Prednisolone (therapeutic use)