[Differentiated thyroid cancer in childhood].

Abstract

Thyroid carcinoma is a rare disease in children, and is mostly of the papillary histological type. Lymph node metastases are frequent at diagnosis, being present in 23 to 74% of the cases and can reveal the cancer in about one fourth of cases. Lung metastases are present at initial diagnosis in 6 to 20% of cases. The main known risk factor for thyroid cancer is a previous history of radiation exposure. Treatment includes surgery with total thyroidectomy and lymph node dissection and radioiodine therapy in case of extensive disease and distant metastases. Life-long thyroxine treatment is given to all patients. Long term prognosis is favourable, but thyroid cancer related deaths have been reported some decades after initial treatment.

• Authors: Sophie Leboulleux, Dana Hartl, Eric Baudin, Martin Schlumberger
• Journal: Bulletin du cancer (Bull Cancer) Vol. 99 Issue 11 Pg. 1093-9 (Nov 2012) ISSN: 1769-6917 [Electronic] France
• Vernacular Title: Cancer differencié de la thyroïde de l'enfant.
• PMID: 23149302 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Iodine Radioisotopes

Topics

• Adolescent
• Carcinoma (genetics, pathology, secondary, therapy)
• Carcinoma, Papillary (genetics, pathology, secondary, therapy)
• Child
• Humans
• Iodine Radioisotopes (therapeutic use)
• Lung Neoplasms (secondary)
• Neoplasm Recurrence, Local (therapy)
• Prognosis
• Rare Diseases (genetics, pathology, therapy)
• Thyroid Neoplasms (genetics, pathology, therapy)
• Thyroid Nodule (genetics, pathology)