[Minute pulmonary meningothelial-like nodules （MPMNs） incidentally detected at surgical biopsy for ground-glass opacity（ GGO）].

Abstract

A 75-year-old woman was followed up at the urology department of our hospital after left nephrectomy for renal cell carcinoma. Chest computed tomography (CT) showed ground-glass opacity in the right lower lobe( S6), 6 mm in size, in December 2010. 3 months later, the tumor was enlarged and she was introduced to our department. Wedge resection was performed to establish giagnosis. Pathological diagnosis was atypical adenomatous hyperplasia( AAH) and many small spindle-shaped cell nests were found at the same tissue. Immunohistochemically, this nest was shown to be minute pulmonary meningothelial-like nodules(MPMNs). MPMNs are asymptomatic small pulmonary nodules incidentally found during pathologic evaluation of pulmonary specimens. Combinations of MPMNs with adenocarcinoma or AAH have been reported, and the genetic relation of MPMNs and AAH is suggested.

• Authors: Takahisa Matsuoka, Hiroko Uematsu, Syotaro Iwakiri, Kazumi Itoi
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 65 Issue 12 Pg. 1063-6 (Nov 2012) ISSN: 0021-5252 [Print] Japan
• PMID: 23117359 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Biopsy
• Female
• Humans
• Incidental Findings
• Lung Neoplasms (pathology)
• Multiple Pulmonary Nodules (diagnostic imaging, pathology)
• Tomography, X-Ray Computed