Clinical impact of switching conventional enzyme immunoassay with nucleic acid amplification test for suspected Clostridium difficile-associated diarrhea.

Abstract	The impact of a new Clostridium difficile nucleic acid amplification test (NAAT) on antibiotic utilization in patients with suspected C difficile infection was assessed. This single-center, cross-sectional study of 270 patients demonstrated that the use of NAAT decreased antibiotic expenditure by reducing prolonged empiric days of therapy in these patients.
Authors	Steven W Johnson, Meganne Kanatani, Romney M Humphries, Daniel Z Uslan
Journal	American journal of infection control (Am J Infect Control) Vol. 41 Issue 4 Pg. 373-5 (Apr 2013) ISSN: 1527-3296 [Electronic] United States
PMID	23040489 (Publication Type: Journal Article)
Copyright	Copyright © 2013 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.
Chemical References	Anti-Bacterial Agents
Topics	Anti-Bacterial Agents (therapeutic use) Clinical Laboratory Techniques (methods) Clostridioides difficile (genetics, immunology, isolation & purification) Clostridium Infections (diagnosis, microbiology) Cross-Sectional Studies Diarrhea (diagnosis, microbiology) Drug Utilization (statistics & numerical data) Female Humans Immunoenzyme Techniques (methods) Male Middle Aged Nucleic Acid Amplification Techniques (methods)

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