A case of bupropion-induced stuttering.

Abstract

OBJECTIVE:

Stuttering is a frequent side effect of many psychotropic drugs, particularly antidepressants.

METHOD:

This is a case report of a woman presenting with stuttering after starting bupropion treatment for her depression.

RESULTS:

The patient's stuttering resolved after discontinuing the bupropion.

CONCLUSION:

Neuroimaging and pharmacological studies have implicated dopamine in the pathophysiology of stuttering. Bupropion's ability to increase dopamine in the frontal cortex was suspected to have been involved in this patient's stuttering. However, further research is needed before causality can be assured.

• Authors: Frank Fetterolf, Michael Marceau
• Journal: General hospital psychiatry (Gen Hosp Psychiatry) 2013 Sep-Oct Vol. 35 Issue 5 Pg. 574.e7-8 ISSN: 1873-7714 [Electronic] United States
• PMID: 22959418 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2013 Elsevier Inc. All rights reserved.

Chemical References

• Antidepressive Agents, Second-Generation
• Bupropion

Topics

• Antidepressive Agents, Second-Generation (adverse effects, therapeutic use)
• Bupropion (adverse effects, therapeutic use)
• Depressive Disorder, Major (drug therapy)
• Female
• Humans
• Middle Aged
• Stuttering (chemically induced)