Abstract | BACKGROUND: METHODS: RESULTS: Median [interquartile range] age at the time of surgery was 40.5 [27.2-46.7] years with a median [interquartile range] BMI of 43.6 [40.9-48.7] kg/m(2). The median baseline levels of TT, SHBG, cFT, LH, and FSH were reduced; levels of E2 were elevated. At 6 months from surgery, the median BMI dropped to 34.8 [31.7-40.5] kg/m(2), TT, SHBG, cFT, LH, and FSH increased, while levels of E2 decreased. The improvement in the sex hormone profile was more evident in younger patients, with a statistically significant difference in cFT following surgery and in the raise of TT and cFT between the groups of patients below and above 35 years. At multivariate analysis, the age was the best predictive factor of the postoperative variations of TT. CONCLUSIONS: These preliminary results confirm the general improvement in sex hormone profile in obese men after bariatric surgery and introduce the age as a possible contributing factor to this improvement.
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Authors | Enrico Facchiano, Stefano Scaringi, Marco Veltri, Jinous Samavat, Mario Maggi, Gianni Forti, Michaela Luconi, Marcello Lucchese |
Journal | Obesity surgery
(Obes Surg)
Vol. 23
Issue 2
Pg. 167-72
(Feb 2013)
ISSN: 1708-0428 [Electronic] United States |
PMID | 22926689
(Publication Type: Journal Article)
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Chemical References |
- Sex Hormone-Binding Globulin
- Testosterone
- Luteinizing Hormone
- Follicle Stimulating Hormone
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Topics |
- Adult
- Age Factors
- Follicle Stimulating Hormone
(blood)
- Gastroplasty
(methods)
- Humans
- Hypogonadism
(blood, etiology, surgery)
- Infertility, Male
(blood, etiology, surgery)
- Luteinizing Hormone
(blood)
- Male
- Middle Aged
- Obesity, Morbid
(blood, complications, surgery)
- Predictive Value of Tests
- Prospective Studies
- Sex Hormone-Binding Globulin
(metabolism)
- Testosterone
(blood)
- Treatment Outcome
- Weight Loss
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