Abstract | AIMS: METHODS AND RESULTS: From January 2002 to June 2009 all patients treated with PPCI were identified from the Western Denmark Heart Registry. We examined mortality according to timing of multivessel PCI: acute procedure, staged procedure during the index hospitalisation, or staged procedure performed within 60 days. The hazard ratio (HR) for death was estimated using a time-dependent Cox regression model, with time of PCI for the non-culprit lesion as the time-dependent variable. The study cohort consisted of 5,944 patients, of whom 4,770 (80%) had single-vessel disease and 1,174 (20%) had multivessel PCI within 60 days. Among 354 (30.2%) patients with acute multivessel PCI, 194 (16.5%) patients with multivessel PCI during the index hospitalisation, and 626 (53.3%) patients with multivessel PCI within 60 days after the index hospitalisation, the adjusted HRs for one-year mortality were 1.53 (95% confidence interval (CI): 1.07-2.18), 0.60 (95% CI: 0.28-1.26), and 0.28 (95% CI: 0.14-0.54), respectively, compared to patients with single vessel disease. CONCLUSIONS: Acute multivessel PCI in patients with STEMI was associated with increased mortality.
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Authors | Lisette Okkels Jensen, Per Thayssen, Dóra Körmendiné Farkas, Mikkel Hougaard, Christian Juhl Terkelsen, Hans-Henrik Tilsted, Michael Maeng, Anders Junker, Jens Flensted Lassen, Erzsébet Horváth-Puhó, Henrik Toft Sørensen, Leif Thuesen |
Journal | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
(EuroIntervention)
Vol. 8
Issue 4
Pg. 456-64
(Aug 2012)
ISSN: 1969-6213 [Electronic] France |
PMID | 22917729
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Aged
- Cohort Studies
- Denmark
- Electrocardiography
- Female
- Humans
- Male
- Middle Aged
- Myocardial Infarction
(mortality, therapy)
- Percutaneous Coronary Intervention
(methods)
- Registries
- Regression Analysis
- Retrospective Studies
- Time Factors
- Treatment Outcome
- Vascular Diseases
(mortality, therapy)
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