Abstract | INTRODUCTION: MATERIAL AND METHODS: We enrolled a total of 73 elderly patients: 45 with AF as the test group and 28 in sinus rhythm as a control group. We assayed serum PPAR-γ receptor protein, high-sensitivity C-reactive protein ( hs-CRP), interleukin-6 (IL-6), and tumour necrosis factor-α (TNF-α). The study protocol and written informed consent were approved by the Ethics Committee of Clinical Research, Peking University First Hospital. RESULTS: The concentration of PPAR-γ receptor protein was lower in AF patients than that in the control group (p < 0.01), and the concentrations of hs-CRP, IL-6, and TNF-α were higher than those in the control group (all p < 0.01). The PPAR-γ level was negatively correlated with hs-CRP, IL-6, and left atrium diameter (LAD) level (all p < 0.05). On logistic regression analysis, PPAR-γ, hs-CRP, TNF-α and LAD level were associated with AF. CONCLUSIONS:
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Authors | Qing Lin, Lina Jia, Yanshu Sun |
Journal | Archives of medical science : AMS
(Arch Med Sci)
Vol. 8
Issue 3
Pg. 471-6
(Jul 04 2012)
ISSN: 1896-9151 [Electronic] Poland |
PMID | 22852002
(Publication Type: Journal Article)
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