Co-factor-enhanced food allergy.

Abstract

BACKGROUND:

Alcohol, exercise or non-steroidal anti-inflamatory drugs (NSAID) are frequently mentioned as amplifiers of food allergic reactions but only individual cases or small series have been previously published.

METHODS:

Descriptive study including 74 cases of suspected co-factor enhanced food allergy, assessed by skin-prick tests, specific IgE and oral challenges.

RESULTS:

Anaphylaxis accounted for 85.1% of reactions. In 99% of cases culprit food allergens were plant-derived, mainly vegetables and cereals. NSAID were involved in 58%, exercise in 52.7% and alcohol in 12.2%. Lipid transfer protein was the most frequently involved allergen.

CONCLUSIONS:

Co-factor enhanced food allergy should be considered when assessing food, alcohol, exercise and NSAID allergic reactions.

• Authors: V Cardona, O Luengo, T Garriga, M Labrador-Horrillo, A Sala-Cunill, A Izquierdo, L Soto, M Guilarte
• Journal: Allergy (Allergy) Vol. 67 Issue 10 Pg. 1316-8 (Oct 2012) ISSN: 1398-9995 [Electronic] Denmark
• PMID: 22845005 (Publication Type: Journal Article)
• Copyright: © 2012 John Wiley & Sons A/S.

Chemical References

• Allergens
• Anti-Inflammatory Agents, Non-Steroidal
• Carrier Proteins
• Plant Proteins
• lipid transfer protein
• Immunoglobulin E

Topics

• Adult
• Allergens (adverse effects, immunology)
• Anaphylaxis (etiology, immunology)
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects, immunology)
• Carrier Proteins (adverse effects, immunology)
• Exercise
• Food Hypersensitivity (etiology, immunology)
• Humans
• Immunoglobulin E (blood)
• Plant Proteins (adverse effects, immunology)
• Skin Tests