[Effect of statins on activity of matrix metalloproteases and serum concentration of cystatin C in patients with various risk of development of ischemic heart disease and in patients after coronary artery bypass surgery].

Abstract

We compared new non-lipid atherosclerosis indexes related to inflammation and macrophage stimulation (serum concentration of cystatin C, matrix metalloproteases and chitotriosidase activity) with common inflammatory (high sensitivity C reactive protein) and lipid markers in elderly persons and patients with atherosclerosis and ischemic heart disease who have undergone coronary bypass surgery.

• Authors: M S Cherkanova, T A Korolenko, I Iu Bravve, T P Gerasimova
• Journal: Kardiologiia (Kardiologiia) Vol. 52 Issue 2 Pg. 23-8 ( 2012) ISSN: 0022-9040 [Print] Russia (Federation)
• PMID: 22792735 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Biomarkers
• Cystatin C
• Hydroxymethylglutaryl-CoA Reductase Inhibitors
• C-Reactive Protein
• Hexosaminidases
• chitotriosidase
• Metalloproteases

Topics

• Adult
• Biomarkers
• C-Reactive Protein (metabolism)
• Coronary Artery Bypass (methods)
• Coronary Vessels (metabolism, physiopathology)
• Cystatin C (blood)
• Female
• Hexosaminidases (metabolism)
• Humans
• Hydroxymethylglutaryl-CoA Reductase Inhibitors (administration & dosage, adverse effects, metabolism)
• Inflammation (drug therapy, metabolism)
• Male
• Metalloproteases (metabolism)
• Middle Aged
• Myocardial Ischemia (metabolism, physiopathology, therapy)
• Plaque, Atherosclerotic (drug therapy, etiology, metabolism)
• Risk Assessment (methods)