Outcome of phacoemulsification in patients with and without Pseudoexfoliation syndrome in Kashmir.

Abstract

BACKGROUND:

The aim of the study is to compare the outcome of phacoemulsification in patients with and without pseudoexfoliation syndrome in Kashmir.

METHODS:

200 patients were prospectively evaluated and divided into 2 groups. Group 1 comprised 100 cases with pseudoexfoliation and Group 2 (control) 100 cases without pseudoexfoliation. Phacoemulsification with posterior chamber intraocular lens implantation was performed by 3 surgeons. Intraoperative and postoperative observations were made in both the groups at regular intervals upto 6 months. A chi square test was used for statistical analysis.

RESULTS:

Patients with pseudoexfoliation were significantly older (P = 0.000), had harder cataract(P = 0.030) and smaller mean pupil diameter(P = 0.000) than the control group. Intraoperative complications were comparable between the 2 groups except the occurrence of zonular dehiscence which was seen in 7% patients of Group 1 compared to 0% in Group 2. Higher postoperative inflammatory response was seen in Group 1(P = 0.000). Decrease in intraocular pressure (IOP) at all postoperative measurements was more in Group 1(P = 0.000). The visual acuity was better in the control group in the early postoperative period (P = 0.029), however the final visual acuity at 6 months was comparable between the 2 groups.

CONCLUSIONS:

Phacoemulsification in presence of pseudoexfoliation necessitates appropriate surgical technique to avoid intraoperative complications. Pseudoexfoliation is associated with higher inflammatory response, significant postoperative IOP drop and satisfactory visual outcome.

• Authors: Aalia R Sufi, Tejit Singh, Asmat Ara Mufti, Mudassar H Rather
• Journal: BMC ophthalmology (BMC Ophthalmol) Vol. 12 Pg. 13 (Jun 06 2012) ISSN: 1471-2415 [Electronic] England
• PMID: 22672195 (Publication Type: Comparative Study, Journal Article)

Topics

• Cataract (complications)
• Exfoliation Syndrome (complications, surgery)
• Female
• Follow-Up Studies
• Humans
• Incidence
• India (epidemiology)
• Intraocular Pressure
• Intraoperative Complications (epidemiology)
• Male
• Middle Aged
• Phacoemulsification (methods)
• Postoperative Complications (epidemiology)
• Prospective Studies
• Time Factors
• Treatment Outcome