Tacrolimus-related hypertrophic cardiomyopathy in an adult cardiac transplant patient.

Abstract

Left ventricular hypertrophy associated with the use of tacrolimus is a rare complication of solid organ transplantation in adult recipients. We present a cardiac transplant recipient who developed severe concentric left ventricular hypertrophy with congestive heart failure related to myocardial hypertrophy on tacrolimus. Hypertrophy improved when the drug was discontinued and replaced with sirolimus.

• Authors: Tong Liu, Yun Gao, Yu-long Gao, Yu-tong Cheng, Su Wang, Zhi-zhong Li, Hai-Bo Zhang, Xu Meng, Chang-sheng Ma, Jian-zeng Dong
• Journal: Chinese medical journal (Chin Med J (Engl)) Vol. 125 Issue 7 Pg. 1352-4 (Apr 2012) ISSN: 2542-5641 [Electronic] China
• PMID: 22613615 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunosuppressive Agents
• Tacrolimus

Topics

• Adult
• Cardiomyopathy, Hypertrophic (chemically induced, diagnosis)
• Female
• Heart Transplantation (adverse effects)
• Humans
• Immunosuppressive Agents (adverse effects, therapeutic use)
• Middle Aged
• Tacrolimus (adverse effects, therapeutic use)