Abstract | OBJECTIVE:
Tonsillectomy is a common procedure with a wide range of described operative techniques and usage of perioperative medications. Single-dose intraoperative dexamethasone has been shown to decrease postoperative nausea and pain and improve return to normal diet. The aim was to determine if a course of oral postoperative steroids would further decrease postoperative morbidity following tonsillectomy in children. STUDY DESIGN: Randomized, placebo-controlled, double-blinded trial. Power analysis recommended 198 participants. SETTING: A university hospital and private hospital. SUBJECTS AND METHODS: RESULTS: The results showed no significant difference between the 2 groups when analyzed for differences in the above variables both overall and at each of the postoperative 10 time points ( pain, P = .478; nausea and vomiting, P = .556; return to normal diet well, P = .234; return to normal activity, P = .668; bedtime, P = .056; number of times awake during the night, P = .593). CONCLUSION:
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Authors | Emily Macassey, Patrick Dawes, Barry Taylor, Andrew Gray |
Journal | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
(Otolaryngol Head Neck Surg)
Vol. 147
Issue 3
Pg. 551-6
(Sep 2012)
ISSN: 1097-6817 [Electronic] England |
PMID | 22585378
(Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Inflammatory Agents
- Prednisolone
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Topics |
- Administration, Oral
- Adolescent
- Anti-Inflammatory Agents
(therapeutic use)
- Child
- Child, Preschool
- Double-Blind Method
- Female
- Humans
- Male
- Postoperative Care
- Postoperative Complications
(drug therapy)
- Prednisolone
(therapeutic use)
- Surveys and Questionnaires
- Tonsillectomy
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