Abstract |
A search of the literature yielded 12 controlled trials on vitamin B6 in the treatment of the premenstrual syndrome. These are discussed with emphasis on methodological aspects. A major drawback of the trials is the limited number of patients included. The existing evidence of positive effects of vitamin B6 is weak, and some well-designed trials with positive results would be needed to change this view.
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Authors | J Kleijnen, G Ter Riet, P Knipschild |
Journal | British journal of obstetrics and gynaecology
(Br J Obstet Gynaecol)
Vol. 97
Issue 9
Pg. 847-52
(Sep 1990)
ISSN: 0306-5456 [Print] England |
PMID | 2242373
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Dose-Response Relationship, Drug
- Female
- Humans
- Premenstrual Syndrome
(drug therapy)
- Pyridoxine
(therapeutic use)
- Research Design
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