[Occult mediastinal node involvement in non-small cell lung cancer after negative uptake on PET/CT: ripples through staging and therapy. Case report and critical review].

Abstract	A 78-years old man, heavy smoker, with a persistent and hacking cough, was diagnosed with an adenocarcinoma of upper lobe of left lung. Clinical stage was defined as cT2N0M0 also on the basis of a negative (18)FDG-PET/TC. After lobectomy, pathological stage resulted, on the contrary, pT2N2M0. Because the considerable incidence of preoperative false negative uptakes of PET/TC for involvement of mediastinal lymph nodes, this case report is highlighted as emblematic, particularly in relation to post-operative treatment of early stage NSCLC.
Authors	L Trodella, F Salvati, M Martelli, P Mattia, P Graziano, E Ippolito
Journal	La Clinica terapeutica (Clin Ter) Vol. 162 Issue 6 Pg. 559-61 ( 2011) ISSN: 1972-6007 [Electronic] Italy
Vernacular Title	Linfonodi mediastinici “occulti” nel NCCLC: ripercussioni della falsa negatività PET/TC sulla stadiazione e sulla terapia. Caso clinico e rassegna critica.
PMID	22262330 (Publication Type: Case Reports, Journal Article, Review)
Topics	Aged Carcinoma, Non-Small-Cell Lung (diagnostic imaging, pathology, secondary, therapy) False Negative Reactions Humans Lung Neoplasms (diagnostic imaging, pathology, therapy) Lymphatic Metastasis Male Mediastinum Multimodal Imaging Neoplasm Staging Positron-Emission Tomography Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!