HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Analysis of stroke after TEVAR involving the aortic arch.

AbstractOBJECTIVE:
To analyse the incidence of stroke after thoracic endovascular aortic repair (TEVAR) for aortic arch disease.
METHODS:
In the last decade, 393 patients received TEVAR at our Institution; in 143 cases the aortic arch was involved (32 zones '0', 35 zones '1' and 76 zone '2'). The left subclavian artery (LSA) was revascularised selectively in 75 cases; the proximal LSA was ligated or occluded with a plug in 55 cases before endograft (EG) deployment.
RESULTS:
Initial clinical success, perioperative mortality, spinal cord ischaemia and stroke in TEVAR patients with or without arch involvement were, respectively, 86.7% vs. 94.4%, 4.2% vs. 2.4%, 2.1% vs. 3.6% and 2.8% vs. 1.2%. The stroke rate was 9.4% (P < 0.02) in 'zone 0', 0% in 'zone 1' and 1.3% in 'zone 2' with scans showing severe atheroma and/or thrombus in all cases. Stroke was observed in patients with 2.6% or without 2.9% LSA revascularisation; however, it was never observed in patients in whom the LSA was occluded before EG deployment and in 4.5% of patients in whom it was patent at the time of EG deployment.
CONCLUSIONS:
Stroke after TEVAR is not infrequent especially when the arch is involved. Careful patient selection together with a strategy to reduce embolisation such as occlusion of supra-aortic trunks before EG deployment may play a beneficial role.
AuthorsG Melissano, Y Tshomba, L Bertoglio, E Rinaldi, R Chiesa
JournalEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (Eur J Vasc Endovasc Surg) Vol. 43 Issue 3 Pg. 269-75 (Mar 2012) ISSN: 1532-2165 [Electronic] England
PMID22240331 (Publication Type: Journal Article)
CopyrightCopyright © 2011 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
Topics
  • Adult
  • Aged
  • Aorta, Thoracic (surgery)
  • Aortic Diseases (epidemiology, surgery)
  • Blood Vessel Prosthesis
  • Blood Vessel Prosthesis Implantation
  • Causality
  • Comorbidity
  • Endovascular Procedures (adverse effects)
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Length of Stay
  • Male
  • Middle Aged
  • Postoperative Complications (classification, epidemiology, etiology)
  • Prospective Studies
  • Prosthesis Design
  • Risk Factors
  • Spinal Cord Ischemia (epidemiology, etiology)
  • Stents
  • Stroke (epidemiology)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: