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A successful combined treatment with dermal substitutes and products of regenerative medicine in a patient affected by extravasation injury from hypertonic solution.

Abstract
In neonatal intensive care units, extravasation is one of the most common injuries occurring in infants as a complication of infusion therapy. These very preterm infants have immature skin which is easily damaged. They often require a longer duration of intravenous therapy, and obtaining intravenous access can be difficult. An invasive treatment should be avoided, whenever possible, particularly for very immature infants. In our Special Operative Unit for ulcers and difficult-to-heal wounds, University of Rome, we successfully treated a premature neonate, who experienced extravasation of hypertonic fluid, using dermal substitutes and products of regenerative medicine.
AuthorsMaria Giuseppina Onesti, Sara Carella, Michele Maruccia, Cinzia Marchese, Pasquale Fino, Nicolò Scuderi
JournalIn vivo (Athens, Greece) (In Vivo) 2012 Jan-Feb Vol. 26 Issue 1 Pg. 139-42 ISSN: 1791-7549 [Electronic] Greece
PMID22210728 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Hypertonic Solutions
Topics
  • Extravasation of Diagnostic and Therapeutic Materials (etiology, therapy)
  • Humans
  • Hypertonic Solutions (adverse effects)
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases (etiology, therapy)
  • Intensive Care Units, Neonatal
  • Male
  • Regenerative Medicine (methods)
  • Skin, Artificial
  • Treatment Outcome

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