Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series.

Abstract

Uveitis treatment involves topical corticosteroids along with cycloplegic-mydriatics. Particularly severe cases may require systemic corticosteroids and immunosuppressive drugs. Vernal keratoconjunctivitis (VKC) treatment consists of a brief period of topical corticosteroids and/or cyclosporine. In patients refractory to traditional treatment, the use of 0.1% topical ophtalmic FK- 506 (tacrolimus) ointment has been occasionally reported.This is the first report of the coexistence of uveitis and VKC. The documented response to topical tacrolimus eyedrop of uveitis and VKC is also of interest, in particular since to our knowledge there are no published reports on its clinical use in uveitis.

• Authors: Andrea Taddio, Rolando Cimaz, Roberto Caputo, Cinzia de Libero, Laura Di Grande, Gabriele Simonini, Francesca Mori, Elio Novembre, Neri Pucci
• Journal: Pediatric rheumatology online journal (Pediatr Rheumatol Online J) Vol. 9 Issue 1 Pg. 34 (Nov 02 2011) ISSN: 1546-0096 [Electronic] England
• PMID: 22047067 (Publication Type: Journal Article)