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Case of secondary syphilis presenting with unusual complications: syphilitic proctitis, gastritis, and hepatitis.

Abstract
We report the first known case of syphilis with simultaneous manifestations of proctitis, gastritis, and hepatitis. The diagnosis of syphilitic proctitis and gastritis was established by the demonstration of spirochetes with anti-Treponema pallidum antibody staining in biopsy specimens. Unusual manifestations of secondary syphilis completely resolved after 4 weeks of antibiotic therapy.
AuthorsEisuke Adachi, Tomohiko Koibuchi, Michio Okame, Hidenori Sato, Kentaro Imai, Shoichi Shimizu, Giichiro Tsurita, Naoki Oyaizu, Aikichi Iwamoto, Takeshi Fujii
JournalJournal of clinical microbiology (J Clin Microbiol) Vol. 49 Issue 12 Pg. 4394-6 (Dec 2011) ISSN: 1098-660X [Electronic] United States
PMID21998411 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
Topics
  • Adult
  • Anti-Bacterial Agents (administration & dosage)
  • Biopsy
  • Gastritis (diagnosis, drug therapy, etiology, pathology)
  • Hepatitis (diagnosis, drug therapy, etiology, pathology)
  • Humans
  • Immunohistochemistry
  • Male
  • Microscopy
  • Proctitis (diagnosis, drug therapy, etiology, pathology)
  • Syphilis (complications, diagnosis, drug therapy, pathology)
  • Treatment Outcome
  • Treponema pallidum (isolation & purification)

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