Resistant trichomoniasis: successful treatment with combination therapy.

Abstract

Metronidazole-resistant vaginal trichomoniasis remains a major therapeutic challenge. Two women with symptomatic metronidazole-resistant trichomoniasis had multiple unsuccessful courses of therapy with a broad array of medications. Both patients finally responded to combination treatment with intravaginal paromomycin cream and high-dose oral tinidazole.

• Authors: Paul Nyirjesy, Jeffrey Gilbert, Laura J Mulcahy
• Journal: Sexually transmitted diseases (Sex Transm Dis) Vol. 38 Issue 10 Pg. 962-3 (Oct 2011) ISSN: 1537-4521 [Electronic] United States
• PMID: 21934573 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiprotozoal Agents
• Antitrichomonal Agents
• Tinidazole
• Metronidazole
• Paromomycin

Topics

• Administration, Intravaginal
• Administration, Oral
• Adult
• Antiprotozoal Agents (pharmacology, therapeutic use)
• Antitrichomonal Agents (administration & dosage, therapeutic use)
• Combined Modality Therapy
• Drug Resistance, Multiple
• Female
• Humans
• Male
• Metronidazole (pharmacology, therapeutic use)
• Middle Aged
• Paromomycin (administration & dosage, therapeutic use)
• Sexual Partners
• Tinidazole (administration & dosage, therapeutic use)
• Treatment Outcome
• Trichomonas Vaginitis (diagnosis, drug therapy, parasitology)
• Trichomonas vaginalis (drug effects, isolation & purification)