Abstract | AIMS: MATERIALS AND METHODS: RESULTS: CONCLUSIONS: This suggests that 11βHSD1 acts as the local regulator of glucocorticoid and its activity in bone was not correlated to systemic corticosterone level.
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Authors | M R Elvy Suhana, H S Farihah, O Faizah, S Ahmad Nazrun, M Norazlina, M Norliza, S Ima Nirwana |
Journal | La Clinica terapeutica
(Clin Ter)
Vol. 162
Issue 4
Pg. 313-8
( 2011)
ISSN: 1972-6007 [Electronic] Italy |
PMID | 21912818
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Biomarkers
- Glucocorticoids
- Plant Extracts
- Glycyrrhizic Acid
- Dexamethasone
- 11-beta-Hydroxysteroid Dehydrogenase Type 1
- Corticosterone
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Topics |
- 11-beta-Hydroxysteroid Dehydrogenase Type 1
(antagonists & inhibitors, metabolism)
- Adrenalectomy
- Animals
- Biomarkers
- Bone Resorption
(chemically induced, enzymology, prevention & control)
- Corticosterone
(blood)
- Dexamethasone
(toxicity)
- Drug Evaluation, Preclinical
- Enzyme Induction
(drug effects)
- Femur
(enzymology)
- Glucocorticoids
(adverse effects)
- Glycyrrhizic Acid
(pharmacology, toxicity)
- Male
- Osteoblasts
(drug effects, enzymology)
- Osteoclasts
(drug effects, enzymology)
- Osteoporosis
(chemically induced, enzymology, prevention & control)
- Phytotherapy
- Piper
- Plant Extracts
(therapeutic use)
- Rats
- Rats, Sprague-Dawley
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