[Biomarkers in rheumatoid arthritis].

Abstract

The search for biomarkers in rheumatoid arthritis (RA) has been the object of interesting research in the past few years, although results have not always been relevant. Several biomarkers, from several different locations (blood, urine, synovial fluid, synovial tissue) and of different nature (autoantibodies, genetic markers, joint remodeling markers), and related to different outcomes, diagnostic and prognostic markers (joint destruction, disability, lack of remission, mortality, response to anti-rheumatic treatment, etc.) have been studied. The present article reviews research only on soluble biomarkers, mainly those in serum, related to the diagnosis and joint destruction in RA.

• Authors: Raimon Sanmartí, José A Gómez-Puerta
• Journal: Reumatologia clinica (Reumatol Clin) Vol. 6S3 Pg. S25-8 (Mar 2011) ISSN: 1885-1398 [Electronic] Spain
• Vernacular Title: Biomarcadores en la artritis reumatoide.
• PMID: 21794768 (Publication Type: English Abstract, Journal Article, Review)
• Copyright: Copyright © 2010 Elsevier España, S.L. All rights reserved.

Chemical References

• Autoantibodies
• Autoantigens
• Biomarkers
• Peptides
• Citrulline

Topics

• Antibody Specificity
• Arthritis, Rheumatoid (diagnosis, drug therapy, metabolism, pathology)
• Autoantibodies (analysis, immunology)
• Autoantigens (immunology)
• Biomarkers (analysis)
• Body Fluids (chemistry)
• Citrulline
• Humans
• Joints (pathology)
• Peptides (immunology)
• Prognosis
• Sensitivity and Specificity
• Treatment Outcome