Abstract | BACKGROUND/AIMS: Peritoneal immune response as well as systemic response was objectively evaluated in laparoscopy-assisted distal gastrectomy (LADG) compared to open distal gastrectomy (ODG). METHODOLOGY: RESULTS: The serum CRP level was significantly higher in the ODG group than in the LADG group (p=0.007) on postoperative day (POD) 1. WBC counts showed no statistically significant difference between the two groups (p=0.105). The rate of cases exhibiting SIRS was significantly higher in the ODG group than in the LADG group (p<0.001). The IL-6 level of drain fluid was significantly higher in the ODG group than the LADG group (p<0.01) on POD1. Although weak correlation between IL-6 on POD1 and blood loss (R=0.38, p=0.0154) was observed, no significant correlation between IL-6 and operation time was noted. CONCLUSIONS: LADG seems to be a lesser traumatic approach for the treatment of gastric cancer.
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Authors | Toshiyuki Natsume, Hiroshi Kawahira, Hideki Hayashi, Yoshihiro Nabeya, Takashi Akai, Daisuke Horibe, Kiyohiko Shuto, Yasunori Akutsu, Kazuyuki Matsushita, Fumio Nomura, Hisahiro Matsubara |
Journal | Hepato-gastroenterology
(Hepatogastroenterology)
2011 Mar-Apr
Vol. 58
Issue 106
Pg. 659-62
ISSN: 0172-6390 [Print] Greece |
PMID | 21661448
(Publication Type: Journal Article)
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Chemical References |
- Interleukin-6
- C-Reactive Protein
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Topics |
- Adult
- Aged
- Aged, 80 and over
- C-Reactive Protein
(analysis)
- Female
- Gastrectomy
(adverse effects)
- Humans
- Interleukin-6
(blood)
- Laparoscopy
(methods)
- Male
- Middle Aged
- Peritonitis
(etiology)
- Stomach Neoplasms
(surgery)
- Systemic Inflammatory Response Syndrome
(etiology)
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