HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Risk factors for conversion and complications after unilateral laparoscopic adrenalectomy.

AbstractBACKGROUND:
Laparoscopic adrenalectomy (LA) is the procedure of choice for surgical management of most benign adrenal tumours, with a reported overall complication rate around 10 per cent. The aim of this study was to determine predictive factors for postoperative complications and conversion to open surgery after unilateral LA.
METHODS:
From 1994 to 2009, consecutive patients undergoing unilateral LA by the lateral transabdominal approach were analysed from a prospectively maintained database. A mass larger than 12 cm in diameter and suspected primary adrenal carcinoma were considered contraindications to LA. Predictive factors for postoperative complications and conversion to open surgery were analysed.
RESULTS:
Some 462 patients were analysed. There were no postoperative deaths. Postoperative complications occurred in 53 patients (11·5 per cent), medical complications in 28, and surgical complications in 33 patients. Six patients underwent reoperation for complications. Multivariable logistic regression analysis showed that conversion to open surgery (odds ratio (OR) 6·20, 95 per cent confidence interval 2·08 to 18·53; P = 0·001) and left-sided tumour (OR 1·89, 1·02 to 3·52; P = 0·044) were independent predictive factors for overall complications. Conversion to open surgery was the only independent predictive factor for medical complications (OR 12·88, 4·21 to 39·41; P = 0·001), and left-sided LA was the only predictive factor for surgical complications (OR 2·22, 1·01 to 4·89; P = 0·047). No factor was predictive of conversion to open surgery.
CONCLUSION:
In this single-institution study, conversion to open surgery and left-sided tumours were independent predictive factors for overall complications, but none of the variables analysed was predictive of conversion.
AuthorsS Gaujoux, S Bonnet, M Leconte, S Zohar, J Bertherat, X Bertagna, B Dousset
JournalThe British journal of surgery (Br J Surg) Vol. 98 Issue 10 Pg. 1392-9 (Oct 2011) ISSN: 1365-2168 [Electronic] England
PMID21618212 (Publication Type: Journal Article)
CopyrightCopyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Topics
  • Adolescent
  • Adrenal Gland Neoplasms (surgery)
  • Adrenalectomy (methods)
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Laparoscopy (methods)
  • Male
  • Middle Aged
  • Postoperative Complications (etiology)
  • Reoperation (statistics & numerical data)
  • Risk Factors
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: