Three cases of osteoma cutis occurring in infancy. A brief overview of osteoma cutis and its association with pseudo-pseudohypoparathyroidism.

Abstract

We report three cases of primary osteoma cutis in children, two of whom (siblings) were associated with Albright's hereditary osteodystrophy (AHO), manifesting as short stature with autosomal dominant inheritance from the father, but no dysmorphic features and no parathyroid hormone (PTH) resistance. Osteoma cutis can manifest as an isolated skin disease, a secondary condition to other skin diseases (such as acne), or in association with several syndromes, including AHO, which in turn may be associated with PTH resistance. The management and prognosis of patients diagnosed with osteoma cutis is determined by whether the skin manifestation has occurred in isolation, in association with a syndrome, or as a secondary skin disease. These three paediatric cases highlight the importance of understanding the aetiology and associations of osteoma cutis in order to appropriately investigate and manage patients who present with this rare skin disease.

• Authors: Susannah Ward, Ella Sugo, Charles F Verge, Orli Wargon
• Journal: The Australasian journal of dermatology (Australas J Dermatol) Vol. 52 Issue 2 Pg. 127-31 (May 2011) ISSN: 1440-0960 [Electronic] Australia
• PMID: 21605097 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists.

Topics

• Bone Neoplasms (complications, diagnosis, pathology)
• Female
• Fibrous Dysplasia, Polyostotic (complications)
• Humans
• Infant
• Male
• Ossification, Heterotopic (complications, diagnosis, pathology)
• Osteoma (complications, diagnosis, pathology)
• Pseudohypoparathyroidism
• Pseudopseudohypoparathyroidism (complications)