Abstract | OBJECTIVE: To report a case of bilateral ovarian fibromas and ovarian leiomyomas in a young patient with Gorlin syndrome and to highlight issues of fertility preservation, ovarian conservation, and preimplantation genetic diagnosis in this population. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 15-year-old female patient with Gorlin syndrome and bilateral ovarian masses. INTERVENTION(S): MAIN OUTCOME MEASURE(S): Preservation of ovarian function, pathologic diagnosis. RESULT(S): CONCLUSION(S): In Gorlin syndrome, ovarian fibromas are a common clinical manifestation. Patients with ovarian involvement may present with complex gynecologic needs and may have decreased fertility potential. Careful surgical management, follow-up, and counseling on options for future fertility should be offered to all patients.
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Authors | Christopher B Morse, Janet F McLaren, Darshan Roy, Evan S Siegelman, Virginia A Livolsi, Clarisa R Gracia |
Journal | Fertility and sterility
(Fertil Steril)
Vol. 96
Issue 1
Pg. e47-50
(Jul 2011)
ISSN: 1556-5653 [Electronic] United States |
PMID | 21565340
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adolescent
- Basal Cell Nevus Syndrome
(complications, diagnostic imaging, surgery)
- Female
- Humans
- Leiomyoma
(complications, diagnostic imaging, surgery)
- Ovarian Neoplasms
(complications, diagnostic imaging, surgery)
- Ovary
(diagnostic imaging, surgery)
- Ultrasonography
- Uterine Neoplasms
(diagnostic imaging, surgery)
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