Marked improvement of headaches and vasomotor symptoms with sympathomimetic amines in a woman with sympathetic hyperalgesia-edema syndrome.

Abstract

PURPOSE:

To determine if relief from various pain conditions with sympathomimetic amines may be a direct effect on pain fibers or related to improvement of edema.

METHODS:

A woman with severe migraine headaches resistant to standard therapy was treated with dextroamphetamine sulfate.

RESULTS:

The headaches markedly improved shortly after treatment as did her vasomotor symptoms. However, in this case the inability to lose weight despite dieting related to edema did not improve.

CONCLUSIONS:

The improvement of pain and vasomotor symptoms in this disorder of the sympathetic nervous system does not seem to necessarily be related to edema causing pain. Sympathomimetic amines may have a direct effect on sympathetic nervous system fibers. Thus, a more appropriate term for this condition instead of idiopathic orthostatic cyclic edema would be sympathetic hyperalgesia-edema syndrome.

• Authors: J H Check, R Cohen
• Journal: Clinical and experimental obstetrics & gynecology (Clin Exp Obstet Gynecol) Vol. 38 Issue 1 Pg. 88-9 ( 2011) ISSN: 0390-6663 [Print] Singapore
• PMID: 21485736 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dextroamphetamine

Topics

• Adult
• Dextroamphetamine (therapeutic use)
• Edema (drug therapy)
• Female
• Humans
• Hyperalgesia (drug therapy)
• Migraine Disorders (drug therapy)