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Kinetic aspects of purine metabolism in cultured fibroblasts. A comparative study of cells from patients overproducing purines due to HGPRT deficiency and PRPP synthetase superactivity.

AuthorsE Zoref, A de Vries, O Sperling
JournalMonographs in human genetics (Monogr Hum Genet) Vol. 10 Pg. 96-9 ( 1978) ISSN: 0077-0876 [Print] Switzerland
PMID214700 (Publication Type: Journal Article)
Chemical References
  • Purines
  • Hypoxanthine Phosphoribosyltransferase
  • Phosphotransferases
  • Ribose-Phosphate Pyrophosphokinase
Topics
  • Cells, Cultured
  • Feedback
  • Fibroblasts (enzymology)
  • Gout (enzymology)
  • Humans
  • Hypoxanthine Phosphoribosyltransferase (deficiency)
  • Kinetics
  • Phosphotransferases (deficiency)
  • Purine-Pyrimidine Metabolism, Inborn Errors (enzymology)
  • Purines (biosynthesis)
  • Ribose-Phosphate Pyrophosphokinase (deficiency)
  • Skin (enzymology)

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