Abstract | OBJECTIVE: METHODS: Patients with incident lupus nephritis ESRD (1995-2006) were identified in the US Renal Data System. Trends in sociodemographic and clinical characteristics were assessed. We tested for temporal changes in standardized incidence rates (SIRs) for sociodemographic groups using Poisson regression. Changes in rates of waitlisting for kidney transplant, kidney transplantation, and all-cause mortality were examined using crude and adjusted time-to-event analyses. RESULTS: CONCLUSION: Our findings indicate that the characteristics of patients with lupus nephritis ESRD and initial therapies have changed in recent years. While SIRs rose in younger patients, among African Americans, and in the South, outcomes did not improve in over a decade of evaluation.
|
Authors | Karen H Costenbader, Amrita Desai, Graciela S Alarcón, Linda T Hiraki, Tamara Shaykevich, M Alan Brookhart, Elena Massarotti, Bing Lu, Daniel H Solomon, Wolfgang C Winkelmayer |
Journal | Arthritis and rheumatism
(Arthritis Rheum)
Vol. 63
Issue 6
Pg. 1681-8
(Jun 2011)
ISSN: 1529-0131 [Electronic] United States |
PMID | 21445962
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
|
Copyright | Copyright © 2011 by the American College of Rheumatology. |
Topics |
- Adolescent
- Adult
- Black People
(statistics & numerical data)
- Body Mass Index
- Child
- Child, Preschool
- Comorbidity
- Diabetes Mellitus
(epidemiology)
- Female
- Humans
- Hypertension
(epidemiology)
- Incidence
- Kidney Failure, Chronic
(epidemiology, therapy)
- Kidney Transplantation
(statistics & numerical data)
- Lupus Nephritis
(epidemiology)
- Male
- Middle Aged
- Prevalence
- Renal Dialysis
(statistics & numerical data)
- Sex Factors
- Treatment Outcome
- United States
(epidemiology)
- Young Adult
|