HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Vaginal birth after cesarean section: risk of uterine rupture with labor induction.

Abstract
We assessed the rate of uterine rupture in patients undergoing labor induction for attempted vaginal birth after cesarean (VBAC). A retrospective study was performed of data from a computerized database. Deliveries from January 1, 1998, to June 30, 2001, in the Southern California Kaiser Permanente system were reviewed and various perinatal characteristics analyzed. A total of 16,218 patients had a prior low transverse cesarean section. Of these, 6832 (42.1%) had a trial of labor. Successful VBAC occurred in 86% of patients with spontaneous onset of labor and 66% of patients with labor induction ( p < 0.001). The uterine rupture rate was not different between patients with spontaneous or induced labor (1.0% versus 1.2%, p = 0.51). Similarly, there was no significant difference between oxytocin or prostaglandin E2 induction (1.4% versus 1.0%, p = 0.59). In our study, labor induction did not appear to increase the risk of uterine rupture in women attempting VBAC.
AuthorsJoseph G Ouzounian, David A Miller, Christy J Hiebert, Leah R Battista, Richard H Lee
JournalAmerican journal of perinatology (Am J Perinatol) Vol. 28 Issue 8 Pg. 593-6 (Sep 2011) ISSN: 1098-8785 [Electronic] United States
PMID21424988 (Publication Type: Journal Article)
Copyright© Thieme Medical Publishers.
Chemical References
  • Oxytocics
  • Oxytocin
  • Dinoprostone
Topics
  • Adult
  • Dinoprostone (adverse effects)
  • Female
  • Humans
  • Labor, Induced (adverse effects)
  • Oxytocics (adverse effects)
  • Oxytocin (adverse effects)
  • Pregnancy
  • Retrospective Studies
  • Trial of Labor
  • Uterine Rupture (epidemiology, etiology)
  • Vaginal Birth after Cesarean (adverse effects)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: