[A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma].

Abstract

We experienced a patient with an ileal artificial anus who suffered from abdominal pain caused by peritoneal dissemination of ovarian cancer, for which slow-release oxycodone was ineffective, but fentanyl patch proved effective. The patient was a 28-year-old female who developed abdominal pain caused by peritoneal dissemination on postoperative day 60 after radical hysterectomy and colostomy. For pain relief, administration of 10-mg slow-release oxycodone and 180-mg loxoprofen sodium was begun. When the dose was increased to 25 mg on postoperative day 240, the slow-release oxycodone in its original form was confirmed in feces from the artificial anus.When the same drug was changed to a fentanyl patch(12. 5 mg/hr), the pain was relieved. A palliative care doctor needs much knowledge regarding the changes in the patient's body with the progress and treatment of cancer, in addition to the drug mechanism.

• Authors: Kazuho Yoshino, Noboru Nishiumi, Ryota Masuda, Yuki Saito, Masayuki Iwazaki, Mikio Mikami, Yutaka Tokuda
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 38 Issue 2 Pg. 325-7 (Feb 2011) ISSN: 0385-0684 [Print] Japan
• PMID: 21368506 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Fentanyl

Topics

• Administration, Cutaneous
• Adult
• Carcinoma (pathology)
• Fatal Outcome
• Female
• Fentanyl (administration & dosage, therapeutic use)
• Humans
• Ileal Neoplasms (secondary)
• Ovarian Neoplasms (complications, pathology)
• Pain (drug therapy, etiology)
• Palliative Care
• Peritoneal Neoplasms (secondary)