Abstract | AIM: METHODS: Male ZDF rats were fed a regular powdered diet with or without JTT-130 as a food admixture (0.01-0.02%) for 6 weeks. Food intake, body weight, blood biochemical parameters, fecal lipid contents, hepatic lipid contents, tissue mRNA levels and glucose utilization in adipose tissues were assessed. An intraperitoneal glucose tolerance test (IPGTT) and histological analysis of the pancreas were performed. RESULTS: CONCLUSIONS:
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Authors | T Hata, Y Mera, T Kawai, Y Ishii, Y Kuroki, K Kakimoto, T Ohta, M Kakutani |
Journal | Diabetes, obesity & metabolism
(Diabetes Obes Metab)
Vol. 13
Issue 7
Pg. 629-38
(Jul 2011)
ISSN: 1463-1326 [Electronic] England |
PMID | 21362121
(Publication Type: Journal Article)
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Copyright | © 2011 Blackwell Publishing Ltd. |
Chemical References |
- Benzamides
- Carrier Proteins
- Glycated Hemoglobin A
- Insulin
- Malonates
- Triglycerides
- diethyl 2-((3-dimethylcarbamoyl-4-((4'-trifluoromethylbiphenyl-2-carbonyl)amino)phenyl)acetyloxymethyl)-2-phenylmalonate
- microsomal triglyceride transfer protein
- Glucagon-Like Peptide 1
- Glucose
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Topics |
- Adipose Tissue
(metabolism)
- Animals
- Benzamides
(pharmacology, therapeutic use)
- Body Weight
- Carrier Proteins
(antagonists & inhibitors)
- Diabetes Mellitus, Experimental
(drug therapy)
- Eating
- Glucagon-Like Peptide 1
(metabolism)
- Glucose
(metabolism)
- Glycated Hemoglobin
- Insulin
(metabolism)
- Lipid Metabolism
(drug effects)
- Male
- Malonates
(pharmacology, therapeutic use)
- Rats
- Rats, Zucker
- Reverse Transcriptase Polymerase Chain Reaction
- Triglycerides
(metabolism)
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