Abstract | BACKGROUND: OBJECTIVES: METHODS: GFR was estimated using the simplified MDRD formula, the Cockcroft-Gault formula, the Jeliffe and the novel CKD-EPI formula. RESULTS: According to the WHO definition the prevalence of anemia in our study was 21%. We observed a progressive decline in GFR and hemoglobin concentration together with a rise in NYHA class. Significant correlations were observed between eGFR and systolic blood pressure, diastolic blood pressure, age, NYHA class, complications of PCI, including bleeding, and major adverse cardiac events. CONCLUSIONS: The prevalence of anemia and chronic kidney disease is high in patients undergoing PCI despite normal serum creatinine, particularly in higher NYHA class. Lower eGFR and hemoglobin are associated with more complications, including bleeding after PCI and higher prevalence of major adverse cardiac events. In patients with risk factors for cardiovascular disease, GFR should be estimated since renal dysfunction and subsequent anemia are important risk factors for cardiovascular morbidity and mortality.
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Authors | Jolanta Malyszko, Hanna Bachorzewska-Gajewska, Jacek Malyszko, Nomy Levin-Iaina, Adrian Iaina, Slawomir Dobrzycki |
Journal | The Israel Medical Association journal : IMAJ
(Isr Med Assoc J)
Vol. 12
Issue 8
Pg. 489-93
(Aug 2010)
ISSN: 1565-1088 [Print] Israel |
PMID | 21337818
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- American Heart Association
- Anemia
(blood, epidemiology)
- Angioplasty, Balloon, Coronary
- Cohort Studies
- Comorbidity
- Coronary Artery Disease
(blood, epidemiology, therapy)
- Creatinine
(blood)
- Female
- Humans
- Kidney Failure, Chronic
(blood, epidemiology)
- Male
- Middle Aged
- New York
- Poland
(epidemiology)
- Prevalence
- Prospective Studies
- Severity of Illness Index
- Sex Distribution
- United States
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