Abstract | BACKGROUND:
Airway management remains a fundamental component of optimal care of the severely injured patient, with endotracheal intubation representing the definitive strategy for airway control. However, multiple studies document an association between out-of-hospital intubation and increased mortality for severe traumatic brain injury. OBJECTIVES: To explore the relationship between out-of-hospital intubation attempts and outcome among trauma patients with Glasgow Coma Scale (GCS) scores ≤ 8 across sites participating in the Resuscitation Outcomes Consortium (ROC). METHODS: The ROC Epistry- Trauma, an epidemiologic database of prehospital encounters with critically injured trauma victims, was used to identify emergency medical services (EMS)-treated patients with GCS scores ≤ 8. Multiple logistic regression was used to explore the association between intubation attempts and vital status at discharge, adjusting for the following covariates: age, gender, GCS score, hypotension, mechanism of injury, and ROC site. Sites were then stratified by frequency of intubation attempts and chi-square test for trend was used to associate the frequency of intubation attempts with outcome. RESULTS: A total of 1,555 patients were included in this analysis; intubation was attempted in 758 of these. Patients in whom intubation was attempted had higher mortality (adjusted odds ratio [OR] 2.91, 95% confidence interval [CI] 2.13-3.98, p < 0.01). However, sites with higher rates of attempted intubation had lower mortality across all trauma victims with GCS scores ≤ 8 (OR 1.40, 95% CI 1.15-1.72, p < 0.01). CONCLUSIONS: Patients in whom intubation is attempted have higher adjusted mortality. However, sites with a higher rate of attempted intubation have lower adjusted mortality across the entire cohort of trauma patients with GCS scores ≤ 8. Coma Scale score.
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Authors | Daniel P Davis, Kent M Koprowicz, Craig D Newgard, Mohamud Daya, Eileen M Bulger, Ian Stiell, Graham Nichol, Shannon Stephens, Jonathan Dreyer, Joseph Minei, Jeffrey D Kerby |
Journal | Prehospital emergency care
(Prehosp Emerg Care)
2011 Apr-Jun
Vol. 15
Issue 2
Pg. 184-92
ISSN: 1545-0066 [Electronic] England |
PMID | 21309705
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
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Topics |
- Adult
- Airway Management
(methods)
- Brain Injuries
(mortality, therapy)
- Emergency Medical Services
(methods)
- Female
- Glasgow Coma Scale
- Humans
- Injury Severity Score
- Logistic Models
- Male
- Prognosis
- Registries
- Risk Assessment
- Treatment Outcome
- United States
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