Generalized acanthosis nigricans related to type B insulin resistance syndrome: a case report.

Abstract

Acanthosis nigricans (AN) is a cutaneous marker for many underlying states such as endocrine abnormality, obesity, certain drugs, and malignancy. Generalized AN is a rare condition and is commonly seen in adults with an underlying malignancy. The type B insulin resistance syndrome, a rare autoimmune disorder, is caused by the autoantibodies to the insulin receptor. Patients typically present with hyperglycemia but also may present with hypoglycemia. We report a rare case of a 36-year-old man with generalized AN and type B insulin resistance syndrome with hypoglycemia.

• Authors: Ki-Heon Jeong, Seung-Joon Oh, Suk Chon, Mu-Hyoung Lee
• Journal: Cutis (Cutis) Vol. 86 Issue 6 Pg. 299-302 (Dec 2010) ISSN: 0011-4162 [Print] United States
• PMID: 21284281 (Publication Type: Case Reports, Journal Article)

Topics

• Acanthosis Nigricans (etiology, immunology)
• Adult
• Autoimmune Diseases (complications, immunology)
• Humans
• Hypoglycemia (etiology)
• Insulin Resistance (immunology)
• Male
• Syndrome