[A surgical (right lobectomy) case of liver metastasis of colon cancer after chemotherapy using mFOLFIRI and cetuximab].

Abstract

A man in his early seventies underwent low anterior resection and partial resection of the liver for the rectal cancer and liver metastasis. However, 4 months after the surgery, he was found to have a liver tumor at S5 and S7 by abdominal CT scan. Then, he underwent chemotherapy (mFOLFOX6), but the metastatic tumor was progressive. We selected FOLFIRI + cetuximab regimen for second-line therapy to resect the metastatic tumor. As the metastatic lesion was become smaller after 4-course of the regimen including cetuximab, we decided to perform a radical resection. We conducted a right lobectomy of the liver, and the tumor was completely resected.

• Authors: Takayoshi Shimobayashi, Naoki Inatsugi, Shusaku Yoshikawa, Tsutomu Masuda, Hideki Uchida, Hiroyuki Kuge, Tomoyo Yokotani, Takaya Yamaguchi, Chihiro Kawaguchi, Kentaro Yamaoka, Mizumi Inagaki, Masaki Matsuoka, Koichi Tatsumi, Tsutomu Saraya, Toshio Otsuji, Yuichi Yamochi, Kozo Yamanishi, Yasunori Enomoto, Akitaka Nonomura, Masayuki Sho, Yoshiyuki Nakajima
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 37 Issue 12 Pg. 2340-2 (Nov 2010) ISSN: 0385-0684 [Print] Japan
• PMID: 21224566 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antibodies, Monoclonal
• Antibodies, Monoclonal, Humanized
• Antineoplastic Agents
• Cetuximab
• Leucovorin
• Fluorouracil
• Camptothecin

Topics

• Adenocarcinoma (drug therapy, pathology, therapy)
• Aged
• Antibodies, Monoclonal (administration & dosage)
• Antibodies, Monoclonal, Humanized
• Antineoplastic Agents (administration & dosage)
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage)
• Camptothecin (administration & dosage, analogs & derivatives)
• Cetuximab
• Colonic Neoplasms (pathology)
• Combined Modality Therapy
• Fluorouracil (administration & dosage)
• Hepatectomy
• Humans
• Leucovorin (administration & dosage)
• Liver Neoplasms (secondary, therapy)
• Male