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Recent advances of radiofrequency ablation for early hepatocellular carcinoma.

Abstract
Hepatocellular carcinoma (HCC) is the third leading cause of death in the malignant neoplastic diseases in the world. Surgical operation is sometimes not indicated because of complicated liver cirrhosis and extrahepatic disorders. Radiofrequency ablation has been developed as a less invasive treatment for HCC since 1999, and long-term outcome has been shown. There are several complications which should be paid attention, and to improve the prognosis, combination treatment with transarterial chemoembolization should be discussed. Overall survival after between RFA and surgical resection should be compared prospectively. Establishment of staging system for treatment allocation of HCC and prevention of HCC recurrence is important issue to be examined.
AuthorsNamiki Izumi
JournalJournal of gastroenterology and hepatology (J Gastroenterol Hepatol) Vol. 26 Suppl 1 Pg. 115-22 (Jan 2011) ISSN: 1440-1746 [Electronic] Australia
PMID21199522 (Publication Type: Journal Article, Review)
Copyright© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
Chemical References
  • Biomarkers, Tumor
Topics
  • Biomarkers, Tumor (blood)
  • Carcinoma, Hepatocellular (mortality, pathology, surgery)
  • Catheter Ablation (adverse effects, trends)
  • Chemoembolization, Therapeutic
  • Disease-Free Survival
  • Hepatectomy
  • Humans
  • Liver Neoplasms (mortality, pathology, surgery)
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Patient Selection
  • Risk Assessment
  • Time Factors
  • Treatment Outcome

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