Abstract | OBJECTIVES: BACKGROUND: Fractures have different etiologies and treatments and may be associated with bone losses. LPT has been shown to improve bone healing. METHODS:
Tibial fractures were created on 15 animals and divided into five groups. LPT started immediately after surgery, repeated at 48-h intervals. Animal death occurred after 30 days. RESULTS: Raman spectroscopy and fluorescence were performed at the surface. Fluorescence data of group IRF + LPT + Biomaterial showed similar readings to those of the group IRF-no bone loss. Significant differences were seen between groups IRF + LPT + Biomaterial and IRF + LPT; IRF + LPT + Biomaterial; and IRF + Biomaterial; and between IRF + LPT + Biomaterial and IRF. CH groups of lipids and proteins readings showed decreased levels of organic components in subjects treated with the association of LPT, biomaterial, and GBR. Pearson correlation showed that fluorescence readings of both CHA and CH groups of lipids and proteins correlated negatively with the Raman data. CONCLUSIONS: The use of both methods indicates that the use of the biomaterials associated with infrared LPT resulted in a more-advanced and higher quality of bone repair in fractures treated with miniplates and that the DIAGNOdent may be used to perform optical biopsy on bone.
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Authors | Antonio L B Pinheiro, Cibelle B Lopes, Marcos T T Pacheco, Aldo Brugnera Jr, Fátima Antonia A Zanin, Maria Cristina T Cangussú, Landulfo Silveira Jr |
Journal | Photomedicine and laser surgery
(Photomed Laser Surg)
Vol. 28 Suppl 2
Pg. S89-97
(Oct 2010)
ISSN: 1557-8550 [Electronic] United States |
PMID | 20929388
(Publication Type: Journal Article)
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Chemical References |
- Biocompatible Materials
- Bone Morphogenetic Proteins
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Topics |
- Animals
- Biocompatible Materials
- Bone Morphogenetic Proteins
(therapeutic use)
- Bone Plates
- Bone Regeneration
(physiology)
- Combined Modality Therapy
- Guided Tissue Regeneration
- Low-Level Light Therapy
- Male
- Rabbits
- Spectrum Analysis, Raman
- Tibial Fractures
(metabolism, surgery, therapy)
- Wound Healing
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