Abstract |
Biofilm formation is often considered the underlying reason why treatment with an antimicrobial agent fails and as an estimated 65-80% of all human infections is thought to be biofilm-related, this presents a serious challenge. Biofilm model systems are essential to gain a better understanding of the mechanisms involved in biofilm formation and resistance. In this review a comprehensive overview of various in vitro and in vivo systems is presented, and their advantages and disadvantages are discussed.
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Authors | Tom Coenye, Hans J Nelis |
Journal | Journal of microbiological methods
(J Microbiol Methods)
Vol. 83
Issue 2
Pg. 89-105
(Nov 2010)
ISSN: 1872-8359 [Electronic] Netherlands |
PMID | 20816706
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Copyright | Copyright © 2010 Elsevier B.V. All rights reserved. |
Topics |
- Animals
- Bacterial Infections
(drug therapy)
- Biofilms
(drug effects, growth & development)
- Disease Models, Animal
- Humans
- Microbiological Techniques
(methods)
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