HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitus.

Abstract
The aims of this study were to investigate the prevalence of ED in Chinese men with type 2 diabetes mellitus, and evaluate the efficacy and safety of sildenafil citrate in these patients. Patients from 42 outpatient diabetes clinics with type 2 diabetes mellitus and ED as defined by the International Index of Erectile Function (IIEF)-5 were studied. Participants with ED received three doses (100 mg each) of sildenafil citrate for use over 3 months. Efficacy of sildenafil citrate was assessed using the IIEF-5 and the Global Efficacy Questionnaire (GEQ). Adverse events were recorded by patients in a daily diary. A total of 5477 participants were evaluated, and 75.2% had ED. Age, duration of diabetes and glycosylated hemoglobin (HbA(1)c) >6.5% were independently and significantly associated with the presence and degree of ED. Patients who received pharmacotherapy (N=389) reported significant improvements. The rate of erections as determined by the GEQ was also significantly improved following treatment. ED is a common complication in Chinese men with type 2 diabetes mellitus, and certain risk factors are associated with the presence of ED and severity. Sildenafil citrate is a safe and effective treatment for these patients.
AuthorsG Yang, C Pan, J Lu
JournalInternational journal of impotence research (Int J Impot Res) 2010 Sep-Oct Vol. 22 Issue 5 Pg. 310-7 ISSN: 1476-5489 [Electronic] England
PMID20811390 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Phosphodiesterase 5 Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate
Topics
  • Adult
  • Aged
  • Asian People (statistics & numerical data)
  • Diabetes Mellitus, Type 2 (ethnology)
  • Erectile Dysfunction (drug therapy, ethnology)
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Phosphodiesterase 5 Inhibitors (therapeutic use)
  • Piperazines (therapeutic use)
  • Prevalence
  • Purines (therapeutic use)
  • Risk Factors
  • Sildenafil Citrate
  • Sulfones (therapeutic use)
  • Surveys and Questionnaires

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: