[Effectiveness of the treatment of patients with pulmonary tuberculosis using a liver protector zixoryn].

Abstract

The treatment of 77 pulmonary tuberculosis patients with zixoryn in the course of chemotherapy resulted in a lower incidence of toxic and allergic reactions and acute hepatitis, and a faster normalization of altered biochemical indices as compared to controls. The rate of cavity closure and sputum conversion was higher than in the controls in addition to a shorter period of in-patient treatment. It is concluded that the liver protector is highly effective in patients with tuberculosis. Besides, it is advisable to use it in the patients with hepatobiliary abnormalities for preventive purposes.

• Authors: V R Mezhebovskiĭ
• Journal: Problemy tuberkuleza (Probl Tuberk) Issue 10 Pg. 32-5 ( 1990) ISSN: 0032-9533 [Print] Russia (Federation)
• Vernacular Title: Effektivnost' lecheniia bol'nykh tuberkulezom legkikh s ispol'zovaniem gepatoprotektora ziksorina.
• PMID: 2080156 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Antitubercular Agents
• Benzhydryl Compounds
• flumecinol

Topics

• Adolescent
• Adult
• Aged
• Antitubercular Agents (administration & dosage, antagonists & inhibitors, toxicity)
• Benzhydryl Compounds (administration & dosage)
• Chemical and Drug Induced Liver Injury (etiology, prevention & control)
• Female
• Humans
• Male
• Microsomes, Liver (drug effects)
• Middle Aged
• Tuberculosis, Pulmonary (drug therapy)