[Changes in immunologic phenotype of cells in hairy cell leukemia].

Abstract

A case of hairy-cell leukemia (HCL) has been described in which the cells of the pathological clone in the course of time lost their surface immunoglobulins and retained membrane markers associated with the T-lymphoid series. It has been suggested that this change in the immunological phenotype of the cells may lead to an erroneous diagnosis of T-cell HCL.

• Authors: L V Muskhelishvili, M V Mandzhgaladze, K Ts Keniia, D M Girdaladze, M M Zodelava
• Journal: Gematologiia i transfuziologiia (Gematol Transfuziol) Vol. 35 Issue 10 Pg. 23-5 (Oct 1990) ISSN: 0234-5730 [Print] Russia (Federation)
• Vernacular Title: Izmenenie immunologicheskogo fenotipa kletok pri volosatokletochnom leĭkoze.
• PMID: 2079195 (Publication Type: Case Reports, Comparative Study, English Abstract, Journal Article)

Chemical References

• Biomarkers, Tumor
• Receptors, Antigen, B-Cell

Topics

• B-Lymphocytes (immunology)
• Biomarkers, Tumor (analysis, immunology)
• Diagnosis, Differential
• Female
• Humans
• Leukemia, Hairy Cell (diagnosis, genetics, immunology)
• Leukemia, T-Cell (diagnosis, immunology)
• Middle Aged
• Phenotype
• Receptors, Antigen, B-Cell (analysis, genetics, immunology)